Accueil

Actualités

Félicitations à Alexandre CASANOVA, groupe REYNOIRD/équipe HAINAUT, Prix Hélène STARK à la Journée Jeunes Chercheurs de la Fondation ARC

Les dernières publications

Equipe ALBIGES-RIZO

Miroshnikova YA, Manet S, Li X, Wickström SA, Faurobert E, Albiges-Rizo C. Calcium signaling mediates a biphasic mechanoadaptive response of endothelial cells to cyclic mechanical stretch. Mol Biol Cell. 2021 Aug 19;32(18):1724-1736.

Vannier DR, Shapeti A, Chuffart F, Planus E, Manet S, Rivier P, Destaing O, Albiges-Rizo C, Van Oosterwyck H, Faurobert E. CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotypeAngiogenesis. 2021 Aug 3. doi: 10.1007/s10456-021-09809-2

Romain Deshayes de Cambronne , Agnès Fouet, Amandine Picart , Anne-Sophie Bourrel, , Cyril Anjou,, Guillaume Bouvier , Cristina Candeias, Abdelouhab Bouaboud, Lionel Costa, Anne-Cécile Boulay, Martine Cohen-Salmon, Isabelle Plu, Caroline Rambaud, Eva Faurobert , Corinne Albigès-Rizo , Asmaa Tazi, Claire Poyart , Julie Guignot  CC17 group B Streptococcus exploits integrins for neonatal meningitis development J Clin Invest. 2021 Mar 1;131(5):e136737.  doi: 10.1172/JCI136737.

Vellino S, Oddou C, Rivier P, Boyault C, Hiriart-Bryant E, Kraut A, Martin R, Coute Y, Knölker HJ, Valverde MA, Albigès-Rizo C, Destaing O. Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes. J Cell Biol. 2021 Feb 1;220(2):e201910079. doi:10.1083/jcb.201910079. PMID: 33399853

Equipe BEDNAR

Abdulkhaleg Ibrahim, Christophe Papin, Kareem Mohideen-Abdul, Stéphanie Le Gras, Isabelle Stoll, Christian Bronner, Stefan Dimitrov*, Bruno P. Klaholz*, Ali Hamiche* Corresponding author MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion Science 372, eabd5581 (2021). DOI: 10.1126/science.abd5581

Equipe BOTTE

Sheena Dass, Serena Shunmugam, Laurence Berry, Christophe-Sebastien Arnold, Nicholas J. Katris, Samuel Duley, Fabien Pierrel, Marie-France Cesbron-Delauw, Yoshiki Yamaryo-Botté, Cyrille Y. Botté Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage Nature communications 2021 May. 14, DOI https://doi.org/10.1038/s41467-021-22956-w

Equipe GUILLUY / LAFANECHERE

Kovalenko, T.A.; Giraud, M.-N.; Eckly, A.; Ribba, A.-S.; Fabienne, P.; Fraboulet, S.; Podoplelova, N.A.; Valentin, J.; Panteleev, M.A.; Gonelle-Gispert, C.; Cook, S.; Lafanechère, L.; Sveshnikova, A.N.; Sadoul, K. Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots. Cells 2021, 10, 1-17.

Gory-Fauré S., Powel R., Jonckheere J., Lanté F., Denarier E., Nguyen C.H., Buisson A., Lafanechère L. and Andrieux A. Pyr1-mediated pharmacological inhibition of LIM Kinase restores synaptic plasticity and normal behavior in a mouse model of schizophrenia. Frontiers in Pharmacology, 2021, doi: 10.3389/fphar.2021.627995

Equipe HAINAUT, groupe MARCHE

Arindam K. Dey, Adrien Nougarède, Flora Clément, Carole Fournier, Evelyne Jouvin-Marche, Marie Escudé, Dorothée Jary, Fabrice P. Navarro and Patrice N. MarcheTuning the Immunostimulation Properties of Cationic Lipid Nanocarriers for Nucleic Acid Delivery Front. Immunol., 23 August 2021 | https://doi.org/10.3389/fimmu.2021.722411

Pfister et al. NASH limits anti-tumour surveillance in immunotherapy-treated HCC  Nature 2021 Apr;592(7854):450-456.  doi: 10.1038/s41586-021-03362-0.  Epub 2021 Mar 24.

Dey, A.K., A. Gonon, E.-I. Pécheur, M. Pezet, C. Villiers, and P.N. Marche. Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells. 2021. Cells 10:96. doi: 10.3390/cells10010096.

Equipe HAKIMI

Dayana C Farhat, Matthew W Bowler, Guillaume Communie, Dominique Pontier, Lucid Belmudes, Caroline Mas, Charlotte Corrao, Yohann Couté, Alexandre Bougdour, Thierry Lagrange, Mohamed-ali Hakimi  Is a corresponding author , Christopher Swale  Is a corresponding author  A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma Elife. 2021 Jul 15;10:e68312.  doi: 10.7554/eLife.68312.  Online ahead of print.

Equipe KHOCHBIN

Mengqing Gao, Jin Wang, Sophie Rousseaux, Minjia Tan, Lulu Pan, Lijun Peng, Sisi Wang, Wenqian Xu, Jiayi Ren, Yuanfang Liu, Martin Spinck, Sophie Barral, Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Denis Puthier, Sandrine Curtet, Lisa Bargier, Zhongyi Cheng, Heinz Neumann, Jian Li, Yingming Zhao, Jian-Qing Mi, Saadi Khochbin, Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution Cell Reports, Volume 36, Issue 4, 2021, 109460, ISSN 2211-1247 https://doi.org/10.1016/j.celrep.2021.109460.

Ekaterina Bourova-Flin, Samira Derakhshan, Afsaneh Goudarzi, Tao Wang, Anne-Laure Vitte, Florent Chuffart, Saadi Khochbin, Sophie Rousseaux, Pouyan Aminishakib The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma Br J Cancer. 2021 Jul 21.  doi: 10.1038/s41416-021-01491-x.  Online ahead of print.

Equipe SLAMA / SIROUX

Jedynak P, Tost J, Calafat AM, Bourova-Flin E, Busato F, Forhan A, et al. 2021. Pregnancy exposure to synthetic phenols and placental DNA methylation - An epigenome-wide association study in male infants from the EDEN cohort. Environ Pollut 118024; doi:10.1016/j.envpol.2021.118024.

Guilbert A, Rolland M, Pin I, Thomsen C, Sakhi A.K, Sabaredzovic A, Slama R, Guichardet K, Philippat C. Associations between a mixture of phenols and phthalates and child behaviour in a French mother-child cohort with repeated assessment of exposureEnviron Int. 2021 Jun 18;156:106697. doi: 10.1016/j.envint.2021.106697.  Online ahead of print.

Ouidir, M.; Seyve, E.; Rivière, E.; Bernard, J.; Cheminat, M.; Cortinovis, J.; Ducroz, F.; Dugay, F.; Hulin, A.; Kloog, I.; Laborie, A.; Launay, L.; Malherbe, L.; Robic, P.-Y.; Schwartz, J.; Siroux, V.; Virga, J.; Zaros, C.; Charles, M.-A.; Slama, R.; Lepeule, J. Maternal Ambient Exposure to Atmospheric Pollutants during Pregnancy and Offspring Term Birth Weight in the Nationwide ELFE Cohort. Int. J. Environ. Res. Public Health 2021, 18, 5806.

Equipe VERDEL, groupe BULET

Ranjan Ramasamy, Vaikunthavasan Thiruchenthooran, Tibutius T P Jayadas,, Thampoe Eswaramohan, Sharanga Santhirasegaram, Kokila Sivabalakrishnan , Arunasalam Naguleswaran,, Marilyne Uzest, Bastien Cayrol, Sebastien N Voisin , Philippe Bulet,  Sinnathamby N Surendran Transcriptomic, proteomic and ultrastructural studies on salinity-tolerant Aedes aegypti in the context of rising sea levels and arboviral disease epidemiology    BMC Genomics 2021 Apr 9;22(1):253.  doi: 10.1186/s12864-021-07564-8.

Evénements

 

Grenoble Host Pathogen Interaction Club

Register here: https://hostpathogen.fr/event/hpi-club-meeting-no4/

-----------------------------------------------------------------------

Les séminaires

               

     De nouvelles dates à venir en septembre 2021 !